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 Gout Care By Smith & Smith Est.1998


   




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Piperine Information and Benefits




Piperine is a compound found in black pepper that has many health benefits. According to Healthline, Piperine might help enhance nutrient absorption, stabilize blood sugar levels, combat cancer cell growth, decrease inflammation, and boost brain function. [1] It has also been shown to increase the absorption of several nutrients and could promote gut health. [2]

Piperine enhances the health benefits of turmeric and other plants by supporting liver function and boasting anti-inflammatory actions. [3] Combining black pepper with turmeric may help increase your body's ability to absorb turmeric's beneficial compounds.

A substance in black pepper called piperine, when combined with curcumin, has been shown to increase bioavailability by 2000%. Similarly, piperine may increase the absorption of selenium, which is a key mineral with powerful anti-inflammatory and cancer-fighting properties.[4]

Science-backed benefits:
  • Powerful Antioxidant
  • Powerful Anti-Inflammatory Properties*
  • May benefit the brain*
  • May improve blood sugar stability*
  • May help low bad (LDL) Cholesterol*
  • May provide cancer-fighting properties*
  • Boost the absorption of nutrients
  • May promote gut health*
  • May offer all-natural pain relief*
  • May reduce appetite*


    • Gout and Piperine Study

     A study published in the National Library of Medicine examined the effect of PIP (Piperine) in immunosuppression of gout inflammation through the regulation of the NLRP3 inflammasome and concluded the following:

    Results:

    "In silico studies of molecular docking demonstrated the activity of PIP as a competitive inhibitor of the mitogen-activated protein kinases/nuclear factor-kappa B axis, upstream of the NLRP3 inflammasome. Analysis of gout models with curative and preventive protocols revealed the immunosuppression activity of PIP by reducing inflammatory symptoms, inhibiting tophus formation resulting from NETosis, reducing cartilage erosion, inhibiting leukocyte exudation, suppressing lipid peroxidation index, and inhibiting the production of C-reactive protein.

    Conclusion:

    The results demonstrate the activity of PIP as an immunosuppressant in gout flare. These findings indicate the potential of PIP as a candidate for prophylactic and therapeutic agent for the treatment of gouty arthritis." [5]

    These are very exciting results given that the Piperine's addition to the GC® GoutCare product was originally intended mainly to help enhance the absorption of the Turmeric (Curcumin) ingredient. To reveal it having its own additional component(s) for Gout suppression takes its ability to the next level of success.



    References:

    1. Healthline.com
    2. Healthline.com
    3. mindbodygreen.com
    4. hopkinsmedicine.org
    5. National Library of Medicine







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    *These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.